Description
Product Details:
| Minimum Order Quantity | 1 Bottle |
| Drug Name | Dolutegravir 50mg |
| Composition | Dolutegravir 50mg |
| Packaging Size | 30 Tablets |
| Active Ingredient | Dolutegravir |
| Packaging Type | Bottle |
| Dosage Form | Tablet |
| Dose/Strength | 50mg |
| Brand | Naivex |
Indication:
Naivex (Dolotegravir) is an FDA-approved medicine. It is used for the treatment and therapeutic approach of HIV infection. Naivex is an integrase inhibitor. By integrating blockade, HIV integrase inhibitors prevent their multiplication and can reduce the amount of HIV in the body.
Mechanism of action:
Naivex (Dolotegravir) is an HIV-1 antiviral agent. It inhibits HIV integration by binding to the active site and thus blocks the transferring step in the integration of retroviral DNA. This is an essential step in the HIV replication cycle and will result in inhibition of viral activity.
Posology and method of administration:
Take Naivex (Dolotegravir) exactly as a health care provider tells you. Naive or experienced treatment with INSTI-naive: 50 mg once a day.
Inducers:
50mg twice a day. INSTITUES experience with certain substitutions associated with INSTI resistance or clinical suspected INSTI
Resistance:
50mg twice a day. Caution: Concomitant administration of dofetilide due to increased potency of dofetilide plasma concentrations and the risk of serious and / or life-threatening events.
Caution
Reported hypersensitivity reactions; characterized by eruptions, changes and sometimes organ dysfunction including injury. Patients with hepatitis B or C underlying hepatitis may be at increased risk for worsening or developing transaminase elevations. Redistribution / accumulation of body fat , Including central obesity, dorsocervical fat extension (buffalo neck), peripheral emphysema, facial emphysema, bladder enlargement and cushingoid appearance. Observed. UGT1A1 and CYP3A transducers (e.g. oxcarbazepine, phenytoin, Phenobarbital, carbamazepine, sunscreen, and rifampicin) decreases Naivex.
Side effects:
The most common adverse reactions with Naivex were headache and fatigue and when used with RBV in decompensated cirrhosis were fatigue, hypersensitivity reactions, Effects on serum liver biochemistry in patients> Hepatitis B or C, Co-Infection, Fat Redistribution, Immune Reconstitution Syndrome, Sleep Problems, Fatigue.
Storage:
The Naivex Store (Dolotegravir) at room temperature
Additional Information:
- Pay Mode Terms: L/C (Letter of Credit),T/T (Bank Transfer),Other
- Port of Dispatch: Delhi, Mumbai
- Production Capacity: 10000
- Delivery Time: 7 days
- Packaging Details: 30 Tablets per bottle
